Lay SummaryOver 7000 Australians are treated for severe trauma every year. Major bleeding in the setting of trauma is associated with poor outcomes and increased rates of death. Severe trauma causes a decrease in the factors within the blood that helps clots to form and stop bleeding. This loss of clotting factors is associated with worse outcomes and it is proposed that early replacement of these factors may reduce bleeding and improve outcomes.
Fibrinogen is one of the key clotting factors that needs to be replaced in severe traumatic bleeding.
Fibrinogen concentrate (FC) is an alternative product used to assist in blood clotting. It is stored in powder form, can be reconstituted at the bedside and given quickly. The study will investigate whether it is quicker to administer FC than cryoprecipitate, which will reduce haemorrhage and improve outcomes. For more information see the link here
FEISTY – Fibrinogen Early In Severe Trauma study.Is it quicker to administer Fibrinogen concentrate than cryoprecipitate?
Violeta is based in the Hunter Valley NSW