Blood platelets play a pivotal role in physiological hemostasis. Disorders of platelet function in general manifest most clearly as either as bleedings or thrombotic disorders hence platelet function testing can be utilized in the analysis of inherited and acquired platelet function disorders.
The Multiplate® Analyzer can detect platelet dysfunction and thus may be used to aid in the diagnosis and clinical management of patients with platelet function disorders
The Multiplate® Analyzer may also be used as a pre-surgical and/or perioperative tool to aid in the prediction of bleeding and for monitoring the efficacy of various types of prohemostatic therapies. Studies have shown that Multiplate® results, used in conjunction with clinical presentation and additional laboratory markers, may be used to help determine timing of surgery after stopping antiplatelet therapy.
Multiplate® results may also be used to assess platelet function perioperative and could be integrated into institution transfusion algorithm to reduce platelet transfusion rates and hence risks from potential complications of platelet transfusion. Reduced platelet transfusions may also help to reduce costs.
Detection of platelet disorders Platelet dysfunction triggered by drugs, diseases or genetic factors may induce a transient or permanent tendency to bleed. The Multiplate® analyzer is able to detect platelet dysfunction. And that makes it an invaluable therapeutic asset for doctors who manage patients with platelet dysfunctions.
Designed to determine and distinguish Sensitivity to platelet disorders is designed into Multiplate®. It detects Glanzmann thrombasthenia, Bernard-Soulier syndrome, ADP receptor defects, and von Willebrand disease (comparable to optical aggregometry). It is also well-suited for the functional determination of heparin-induced thrombocytopenia in whole blood.
Whole blood, no sample processing
Small sample volume (300 µl)
Mini test cells use 175 µl of whole blood; smallest volume requirement for aggregometry testing. Ideal for pediatric platelet research or animal platelet studies.
Up to 30 tests per hour
Interactive electronic pipetting
5 independent channels for parallel testing
Specific and sensitive reagents
Standardized test procedures
Open system for research applications
New tests can be defined in the system software
More than 600 Medline publications 2006 and consensus papers with Multiplate and published guidelines for PFT