Comprehensive menu of reagents
ADPtest Assay for the quantitative in vitro determination of platelet function following stimulation of the platelet adenosine diphosphate (ADP) receptors. The ADPtest assay may be used to detect an inhibition of the P2Y12 receptor, as well as an inhibition or absence of the GpIIb/IIIa receptor
ASPItest Assay for the quantitative in vitro determination of platelet function triggered by arachidonic acid. The ASPItest may be used to detect an inhibition of the platelet cyclooxygenase, as well as an inhibition or absence of the GpIIb/IIIa receptor
TRAPtest Assay for the quantitative in vitro determination of platelet function triggered by TRAP-6. Thrombin receptor activating peptide-6 (TRAP-6) is a potent platelet activator and stimulates platelet aggregation via the thrombin receptor PAR-1. The TRAPtest may be used to detect platelet function triggered via the thrombin receptor without triggering fibrin formation
COLtest Assay for the quantitative in vitro determination of platelet function triggered by collagen
RISTOtest Assay for the quantitative in vitro determination of von Willebrand Factor (vWF)- and glycoprotein Ib (GpIb)-dependent platelet aggregation
ASA reagent Inhibitor of cyclooxgenase. Addition of ASA reagent to the blood sample leads to reduced aggregation responses in the ASPItest and the COLtest
GpIIbIIIa antagonist reagent Inhibitor of the platelet GpIIbIIIa receptor. Addition of the GpIIbIIIa reagent to the blood sample leads to strongly reduced aggregation in the TRAPtest
Liquid Control Set Quality control for electrical signal in impedance aggregometry based on the analysis of an artificial liquid control material
Hirudin blood collection tubes: Recombinant hirudin anticoagulates the blood by direct thrombin inhibition and allows for platelet function analysis under physiological calcium concentrations.
- TRAPtest triggers the thrombin receptor. It is insensitive to Aspirin induced cyclooxygenase inhibition, and has little sensitivity to ADP receptor inhibitors like clopidogrel.
- ASPItest is highly sensitive to Aspirin but not affected by ADP receptor inhibition e.g. by clopidogrel.
- ADPtest is sensitive to ADP receptor inhibitors but not affected by cyclooxygenase inhibition.
- ADPtest HS has an increased sensitivity towards clopidogrel due to the addition of prostaglandin E1, and is especially used for the analysis of heparin blood.
- RISTOtest is the only Multiplate test which is sensitive to disorders of vWF..