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Dilutional Coagulopathy and Fibrinogen–FXIII Replacement

Fibrinogen and FXIII should be considered together as a clot-stability unit

Defines an empirical fibrinogen-to-FXIII replacement ratio to restore clot stability after severe haemodilution.

Restoring Clot Stability in Dilutional Coagulopathy

Related Resources

Customer Brief

Customer brief defining an empirical fibrinogen–FXIII replacement ratio.

LinkedIn Post

LinkedIn post introducing the dilutional coagulopathy fibrinogen–FXIII work.

Journal Article

Alomar-Dominguez C, Bauer M, Fries D ...
Defining a fibrinogen-to-factor XIII replacement ratio in an in-vitro model of dilutional coagulopathy
Thrombosis Research, 2026; 262

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