Viscoelastic Point-of-Care Testing (ClotPro®) to Guide Intravenous Thrombolysis in Acute Ischemic Stroke Patients on DOACs

A recent proof-of-concept study published in Neurol. Int. 2025 has assessed the effectiveness of ClotPro® viscoelastic point-of-care testing in quickly evaluating DOAC activity among acute ischemic stroke patients to assist in intravenous thrombolysis (IVT) decisions.

ClotPro® successfully identified 37.5% (15 patients) as having subtherapeutic levels, allowing 7 of them to undergo IVT. This highlights the potential of real-time whole blood hemostatic assessment at the point of care to broaden IVT eligibility in cases where patient history is ambiguous. This advancement represents a significant stride towards enhancing the safety and efficiency of stroke care decision-making.

https://pubmed.ncbi.nlm.nih.gov/40710906/

hashtag#Stroke hashtag#DOAC hashtag#ClotPro hashtag#AcuteCare hashtag#PointOfCare hashtag#PoCT hashtag#Multiclot