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Clinical Resources

Practical summaries of emerging evidence in coagulation diagnostics, fibrinolysis, anticoagulation, and viscoelastic testing. Explore customer briefs, visual explainers, and publication-based insights designed for clinical, laboratory, and research use

 

For healthcare professionals in Australia. Educational use only.

Featured Clinical Briefs

ICU clinicians have a bedside number that tells them whether their fibrinolysis is recoverable — and whether today's treatment is working

Grading of fibrinolysis resistance in sepsis Tags: ClotPro | ICU | SEPSIS|

Personalised Thrombolysis for Acute PE in ICU

Viscoelastometry-guided, low-dose systemic thrombolysis for high- and intermediate-high-risk pulmonary embolism. Tags: ClotPro | PE | ICU | Thrombolysis

Monitoring unfractionated heparin in ECMO and cardiac surgery: the search for a valid reference standard

The authors argue that anti-Xa assays are being used as if validated when they are not. Tags: ClotPro | ICU | UFH| ECMO

Interpreting Low ML in Viscoelastometry

Why low maximum lysis should not automatically be equated with fibrinolysis shutdown. Tags: ClotPro | Fibrinolysis | ML | Critical Care

UFH Monitoring in Critically Ill Patients

ClotPro IN/HI-Test, aPTT and Anti-Xa activity in ICU patients receiving unfractionated heparin. Tags: ClotPro | ICU | UFH | ECMO

Triple-Bolus vs Continuous TXA in CABG – Does Dosing Strategy Matter?

We should tailor TXA dosing to the patient’s actual coagulation profile Tags: ClotPro | ICU | TXA| CARDIAC

Fibrinogen first is only part of the story.

We should increasingly think of fibrinogen and FXIII when aiming to restore clot stability Tags: ClotPro | ICU | PBM|

Functional Aspects of Fibrin Structure Alterations by Tranexamic Acid in the Inhibition of Fibrinolysis

Insight into prophylactic TXA the importance of context in optimizing its clinical use. Tags: ClotPro | ICU | TXA | FIBRINOLYSIS

DOAC Dipstick Testing in Acute Stroke: In Regional
Australia

designed to test whether rapid urine DOAC screening can reliably support acute stroke decisionmaking Tags: Doasense | ICU | STROKE

Clinical Infographics

Visual summaries of the articles featured in our Clinical Briefs. Each infographic details  the key findings, clinical context, and practical takeaways into a single reference designed for quick use at the bedside, in teaching, and in clinical discussions.

Restoring Clot Stability

Restoring Clot Stability

Fibrinogen alone” is often not enough – FXIII depletion is real and clinically relevant.

Grading Dynamic Fibrinolysis Resistance in Sepsis

Grading Dynamic Fibrinolysis Resistance in Sepsis

A bedside grading system using TPA-LT/FIBA₁₀ that identifies three fibrinolysis endotypes in sepsis — associated with disease severity, organ failure and 28-day outcomes.

HVD-ClotPro-Fibrinolysis

HVD-ClotPro-Fibrinolysis

At-a-glance summary "Is physiological lysis really plasmin-mediated fibrinolysis?" – reproduced from materials accompanying Smudla et al., Diagnostics 2026.

Personalised Thrombolysis for Acute PE in the ICU

Personalised Thrombolysis for Acute PE in the ICU

Single-centre randomised feasibility trial of ClotPro-guided, individualised low-dose thrombolysis vs standard fixed-dose rtPA in high- and intermediate-high-risk pulmonary embolism.

Therapeutic UFH — Critical Points in Monitoring & Dosing

Therapeutic UFH — Critical Points in Monitoring & Dosing

Narrative review highlighting unresolved evidence gaps: aPTT vs anti-Xa limitations, uncertainty in the 0.3–0.7 IU/mL target, and why apparent heparin resistance often reflects complexity rather than true resistance.

TXA & Fibrin Structure

TXA & Fibrin Structure

Mechanistic study showing how the timing of tranexamic acid and the clot microenvironment shape its antifibrinolytic effect — including paradoxical acceleration of lysis in prophylactic models.

UFH Monitoring in ECMO & Cardiac Surgery — The Search for a Valid Reference Standard

UFH Monitoring in ECMO & Cardiac Surgery — The Search for a Valid Reference Standard

Why anti-Xa is useful but not universally valid: assay dependence, dextran sulphate effects, and how CPB, ECMO and post-protamine contexts change interpretation.

TXA in CABG

TXA in CABG

Tripple-Bolus vs Continuous TXA in CABG – Does Dosing Strategy Matter

DOAC testing in stroke

DOAC testing in stroke

Rapid urine DOAC screening in strokes

Product Document Library

Access current product inserts, instructions for use and supporting documentation for Haemoview-supported coagulation technologies.

Product inserts for viscoelastic testing assays and consumables.

Cup & Pin

Single Cup & Pin- Durable polymer design with surface treatment for excellent hemocompatibility and consistent torque transfer

EX-Assay

Rapid overview of coagulation activation.

FIB-Assay

Functional fibrinogen measurement.

IN-Assay

Intrinsic activation sensitive to heparin.

HI-Assay

Intrinsic pathway with heparin neutralisation.

RVV-Assay

Single Cup & Pin- Durable polymer design with surface treatment for excellent hemocompatibility and consistent torque transfer

TPA-Assay

Single Cup & Pin- Durable polymer design with surface treatment for excellent hemocompatibility and consistent torque transfer

AP-Assay

Tests whole blood coagulation with fibrinolysis inhibition.

ECA-Assay

High sensitivity assay for the detection of dabigatran.

QC-1

The QC1 is a quality control material based on normal plasma for
in-vitro diagnostic professional use, intended for internal quality
control of reagents for viscoelastometry analysis

QC-2

The QC2 is a quality control material based on normal plasma
with the addition of an anticoagulant for in-vitro diagnostic
professional use, intended for internal quality control of reagents
for viscoelastometry analysis.

Quality Control Target range certificates

QC 1

LOT C11A54C00

LOT C11A61C00

QC 2

LOT C23761C00

Want to learn more or discuss MultiClot for your institution or research project? Our team is here to help.

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